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Article

Orthobunyavirus neurovirulence is a complex trait involving all three genome segments

2025-09-16

Abstract excerpt

<h4>ABSTRACT</h4> La Crosse orthobunyavirus (LACV) is a tri-segmented negative sense RNA virus and is the leading cause of pediatric arboviral encephalitis in the USA. The viral factors that mediate LACV’s ability to replicate and cause damage and disease in the brain (neurovirulence) are not fully understood. We previously characterized the neurovirulence of LACV and closely related Inkoo virus (INKV) and discov...

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Identifiers and source

Literature Corpus work
10cca93a-dab4-585b-84d5-123555222123
DOI
10.1101/2025.09.16.676581
Open publication

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Orthobunyavirus neurovirulence is a complex trait involving all three genome segmentsDOI 10.1101/2025.09.16.676581
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