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Article

Attenuation hotspots in neurotropic human astroviruses

17 Jul 2023

Abstract excerpt

During the last decade, the detection of neurotropic astroviruses has increased dramatically. The MLB genogroup of astroviruses represents a genetically distinct group of zoonotic astroviruses associated with gastroenteritis and severe neurological complications in young children, the immunocompromised, and the elderly. Using different virus evolution approaches, we identified dispensable regions in the 3' end of...

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PMID: 37459343
DOI: 10.1371/journal.pbio.3001815

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