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Pre-existing SIV infection increases expression of T cell markers associated with activation during early <i>Mycobacterium tuberculosis</i> co-infection and impairs TNF responses in granulomas

2020-12-14

Abstract excerpt

Tuberculosis (TB) is the leading infectious cause of death among people living with HIV (PLHIV). PLHIV are more susceptible to contracting Mycobacterium tuberculosis ( Mtb ) infection and often have worsened TB disease. Understanding the immunologic defects caused by HIV and the consequences it has on Mtb co-infection is critical in combating this global health epidemic. We previously established a model of sim...

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Literature Corpus work
10c9a2d3-255a-58a7-aa67-f716114c0ae3
DOI
10.1101/2020.12.14.422668
Open publication

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