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Article

Attrition of TCR Vα7.2+ CD161++ MAIT cells in HIV-tuberculosis co-infection is associated with elevated levels of PD-1 expression.

PloS one - 1 Jan 2015

Saeidi Alireza, Tien Tien Vicky L, Al-Batran Rami, Al-Darraji Haider A, Tan Hong Y, Yong Yean K, Ponnampalavanar Sasheela, Barathan Muttiah, Rukumani Devi V, Ansari Abdul W, Velu Vijayakumar, Kamarulzaman Adeeba, Larsson Marie, Shankar Esaki M

Abstract excerpt

Mucosal-associated invariant T (MAIT) cells are evolutionarily conserved antimicrobial MR1-restricted CD8(+) T cells co-expressing the semi-invariant TCR Vα7.2, and are numerous in the blood and mucosal tissues of humans. MAIT cells appear to undergo exhaustion in chronic viral infections. Howeve...

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Source

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Identifiers

PMID: 25894562
DOI: 10.1371/journal.pone.0124659
PMCID: PMC4403924

Genes

CCR6
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25894562-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Attrition of TCR Vα7.2+ CD161++ MAIT cells in HIV-tuberculosis co-infection is associated with elevated levels of PD-1 expression.PMID 25894562Read ↗

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