Article

Differentially methylated regions (DMRs)-dependent cfDNA fragmentation profile for diagnosis of breast cancer

2021-04-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Breast cancer, the most common malignancy in women, has been proved to have both altered plasma cell-free DNA (cfDNA) methylation and fragmentation profile, nevertheless, simultaneously detecting both of them for breast cancer diagnosis has never been reported. Moreover, although it is known that fragmentation pattern of cfDNA is determined by nuclease digestion...

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Literature Corpus work: 10b7d0ab-610f-53e0-bb0a-c9967115f7a8
DOI: 10.21203/rs.3.rs-403375/v1

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