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FinaleDB: a browser and database of cell-free DNA fragmentation patterns

2020-08-24

Abstract excerpt

<h4>Summary</h4> Circulating cell-free DNA (cfDNA) is a promising biomarker for the diagnosis and prognosis of many diseases, including cancer. The genome-wide non-random fragmentation patterns of cfDNA are associated with the nucleosomal protection, epigenetic environment, and gene expression in the cell types that contributed to cfDNA. However, current progress on the development of computational methods and un...

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Literature Corpus work
17d19a07-1d36-5bbd-9fc2-3a2a080a74b4
DOI
10.1101/2020.08.18.255885
Open publication

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