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Development and validation of a blood-based assay for gastric cancer early detection: A multidimensional analysis of cell-free DNA whole methylome sequencing—protocol for an observational, case‒control study

2023-04-06

Abstract excerpt

<h4>Background: </h4> Cancer-related features in cell-free DNA (cfDNA) fragments have gradually been identified and play essential roles in noninvasive early cancer detection. Integrated analysis of several cfDNA features has enhanced detection sensitivity compared to single features. To facilitate early diagnosis of gastric cancer, an assay based on assessing genomic-scale methylation and fragmentation profiles o...

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Literature Corpus work: 2fc5efc4-ff89-5446-9c15-9e06e5de1ba5
DOI: 10.21203/rs.3.rs-2730560/v1

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