Article

Inhibition of Multiple Staphylococcal Growth States by a Small Molecule that Disrupts Membrane Fluidity and Voltage

2024-01-21

Abstract excerpt

New molecular approaches to disrupting bacterial infections are needed. The bacterial cell membrane is an essential structure with diverse potential lipid and protein targets for antimicrobials. While rapid lysis of the bacterial cell membrane kills bacteria, lytic compounds are generally toxic to whole animals. In contrast, compounds that subtly damage the bacterial cell membrane could disable a microbe, facilita...

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Literature Corpus work: 10afa88e-e7de-5687-b684-b38e2bb61751
DOI: 10.1101/2024.01.17.576101

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