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Article

Anti-staphylococcal activity and mode of action of clofazimine.

The Journal of antimicrobial chemotherapy - 1 Mar 2004

Oliva Brunello, O'Neill Alexander John, Miller Keith, Stubbings William, Chopra Ian

Abstract excerpt

OBJECTIVES: Infections caused by Staphylococcus aureus might be treated with agents whose primary indications are for other infections. Clofazimine, an established anti-mycobacterial drug, could be such a candidate. However, the anti-staphylococcal properties of clofazimine have not been fully described and its mode of action, possibly involving inhibition of both RNA polymerase and a membrane-located target, has...

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Identifiers

PMID: 14762055
DOI: 10.1093/jac/dkh114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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