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Carotenoid-Related Alteration of Cell Membrane Fluidity Impacts <i>Staphylococcus aureus</i> Susceptibility to Host Defense Peptides

30 Nov 2010

Abstract excerpt

Carotenoid pigments of Staphylococcus aureus provide integrity to its cell membrane (CM) and limit oxidative host defense mechanisms. However, the role of carotenoids in staphylococcal resistance to nonoxidative host defenses has not been characterized. The current study examined the relationship among CM carotenoid content, membrane order, and in vitro susceptibility to daptomycin or to prototypic...

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PMID: 21115796
DOI: 10.1128/aac.00680-10

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