Article

ApoE Alzheimer’s Disease Aβ-amyloid plaque morphology varies according to APOE isotype

2023-02-08

Abstract excerpt

<h4>Background: </h4> The apolipoprotein E (APOE, gene; apoE, protein) ε4 allele is the most common identified genetic risk factor for typical late-onset sporadic Alzheimer’s disease (AD). Each APOE ε4 allele roughly triples the relative risk for AD compared to that of the reference allele, APOE ε3. <h4>Methods: </h4>: We have employed hyperspectral fluorescence imaging with an amyloid-specific, conformation-sensi...

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Literature Corpus work: 109521db-7461-5768-bc17-b9e7531fd266
DOI: 10.21203/rs.3.rs-2524641/v1

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