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CMAS dampens anti-tumor immunity and associates with response to neoadjuvant immunotherapy in melanoma

2026-04-29

Abstract excerpt

Identifying immune-regulatory pathways to predict response is crucial for the efficacy of immune checkpoint blockade (ICB) immunotherapies. Sialylation is upregulated in tumor cells and modulates immune responses in cancer, yet its impact on patient clinical outcome and the spatial organization of the tumor microenvironment remain unclear. Here, using publicly available single-cell RNA sequencing data we show that...

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Literature Corpus work
107c5ac1-2b6f-5766-aff2-5fdf997058a7
DOI
10.64898/2026.04.27.719251
Open publication

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CMAS dampens anti-tumor immunity and associates with response to neoadjuvant immunotherapy in melanomaDOI 10.64898/2026.04.27.719251
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