Article

Tumor sialylation controls effective anti-cancer immunity in breast cancer

2023-09-22

Abstract excerpt

Breast cancer is the most common cancer among women. However, the use of immune checkpoint inhibitors, that have revolutionized treatment of multiple cancers, unfortunately remain largely ineffective in most breast cancer patients. Here, we report the most comprehensive glycoproteome map in breast tumor cells, pointing to a key role of sialic acid modifications in mammary cancer. Genetic and pharmacologic inhibiti...

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Literature Corpus work: 41881ef7-30fe-516f-ab07-ecdfb99edee0
DOI: 10.1101/2023.09.20.558571

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