Article
Effects of innate immune activation by Toll-like receptor agonists on ethanol consumption and preference in FVB/NJ x C57BL/6J hybrid mice
2025-05-10
Abstract excerpt
Excessive alcohol (ethanol) consumption is a hallmark of alcohol use disorder (AUD). Activation of innate immune system and proinflammatory signaling in the brain may play a key role in promoting alcohol consumption and development of AUD in humans. Innate immune activation by toll-like receptor (TLR) agonists in rodents is associated with release of proinflammatory cytokines and changes in alcohol consumption, an...
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Identifiers and source
- Literature Corpus work
- 102456fb-07e8-5bf3-bff2-7cc5fb8a0d41
- DOI
- 10.1101/2025.05.06.652465
