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Article

Restricted immunological and cellular pathways are shared by murine models of chronic alcohol consumption

12 Feb 2020

Abstract excerpt

Abstract Murine models of chronic alcohol consumption are frequently used to investigate alcoholic liver injury and define new therapeutic targets. Lieber-DeCarli diet (LD) and Meadows-Cook diet (MC) are the most accepted models of chronic alcohol consumption. It is unclear how similar these models are at the cellular, immunologic, and transcriptome levels. We investigated the common and specific pathways of LD...

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PMID: 32051453
DOI: 10.1038/s41598-020-59188-9

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