Article

A Chaperonin Complex Regulates Organelle Proteostasis in Malaria Parasites

2024-11-13

Abstract excerpt

The apicoplast of Plasmodium parasites serves as a metabolic hub that synthesize essential biomolecules. Like other endosymbiotic organelles, 90% of the apicoplast proteome is encoded by the cell nucleus and transported to the organelle. Evidence suggests that the apicoplast has minimal control over the synthesis of its proteome and therefore it is unclear how organelle proteostasis is regulated. Here, we identif...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4b178506-0595-5de8-867d-806af2ba8751
DOI: 10.1101/2024.11.13.623364

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Chaperonin Complex Regulates Organelle Proteostasis in Malaria ParasitesDOI 10.1101/2024.11.13.623364Read

The mitosome, a novel organelle related to mitochondria in the amitochondrial parasite <i>Entamoeba histolytica</i>Semantic proximity Read

The heat shock protein 40 family of the malaria parasite <i>Plasmodium falciparum</i>Semantic proximity Read

PfClpC Is An Essential Clp Chaperone Required For Plastid Integrity And Clp Protease Stability In <i>Plasmodium falciparum</i>Semantic proximity Read

The Bacterial ClpXP-ClpB Family is Enriched with RNA-Binding Protein ComplexesSemantic proximity Read

Essential role for HSP40 in asexual replication and thermotolerance of malaria parasitesSemantic proximity Read

The Hsp70/Hsp90 Co-Chaperone Hop/Stip1 Shifts the Proteostatic Balance from Folding Towards DegradationSemantic proximity Read

PfClpC Is an Essential Clp Chaperone Required for Plastid Integrity and Clp Protease Stability in Plasmodium falciparum.Semantic proximity Read

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.Semantic proximity Read

The Hsp90 chaperone system from the African trypanosome, <i>Trypanosoma brucei</i>Semantic proximity Read

CaaX-like protease of cyanobacterial origin is required for complex plastid biogenesis in malaria parasitesSemantic proximity Read

Chaperone-mediated assembly of the proteasome core particle – recent developments and structural insightsSemantic proximity Read

Chaperonin-assisted protein folding: a chronologue.Semantic proximity Read