Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic ablation of plasmoDJ1, a multi-activity enzyme, attenuates parasite virulence and reduces oocyst production.

The Biochemical journal - 15 Jul 2014

Singhal Neha, Mastan Babu S, Kumar Kota Arun, Sijwali Puran Singh

Abstract excerpt

Malaria parasites must respond to stresses and environmental signals to perpetuate efficiently during their multistage development in diverse environments. To gain insights into the parasite's stress response mechanisms, we investigated a conserved Plasmodium protein, which we have named plasmoDJ1 on the basis of the presence of a putative cysteine protease motif of the DJ-1/PfpI superfamily, for its activities,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Artemisinins
Share to Cysteine Endopeptidases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Knockout Techniques

Share to Oocysts

Share to Plasmodium berghei

Share to Plasmodium falciparum

Share to Protozoan Proteins

Share to Rats, Wistar

Source

Identifiers

PMID: 25091419
DOI: 10.1042/BJ20140051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic ablation of plasmoDJ1, a multi-activity enzyme, attenuates parasite virulence and reduces oocyst production.PMID 25091419Read ↗

A druggable oxidative folding pathway in the endoplasmic reticulum of human malaria parasitesSemantic proximity Read ↗

PfClpC Is An Essential Clp Chaperone Required For Plastid Integrity And Clp Protease Stability In <i>Plasmodium falciparum</i>Semantic proximity Read ↗

Structural Biology of the DJ-1 Superfamily.Semantic proximity Read ↗

Plasmodium falciparum Molecular Chaperones: Guardians of the Malaria Parasite Proteome and Renovators of the Host ProteomeSemantic proximity Read ↗

PfClpC Is an Essential Clp Chaperone Required for Plastid Integrity and Clp Protease Stability in Plasmodium falciparum.Semantic proximity Read ↗

A Genome-wide Chromatin-associated Nuclear Peroxiredoxin from the Malaria Parasite Plasmodium falciparumSemantic proximity Read ↗

A mutagenesis screen for essential plastid biogenesis genes in human malaria parasitesSemantic proximity Read ↗

The heat shock protein 40 family of the malaria parasite <i>Plasmodium falciparum</i>Semantic proximity Read ↗

A Unique Protein Phosphatase with Kelch-Like Domains (PPKL) in Plasmodium Modulates Ookinete Differentiation, Motility and InvasionSemantic proximity Read ↗

Knockout studies reveal an important role of Plasmodium lipoic acid protein ligase A1 for asexual blood stage parasite survival.Semantic proximity Read ↗

The role of metacaspase 1 in Plasmodium berghei development and apoptosis.Semantic proximity Read ↗

Plasmodial HSP70s are functionally adapted to the malaria parasite life cycleSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.