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CrosstalkIn: Crosstalk-aware inference of tumor microenvironment cell infiltration

2026-05-13

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<title>Abstract</title> <p>Background The tumor microenvironment (TME) is a complex ecosystem whose cellular composition and interactions shape tumor progression, therapeutic response, and patient prognosis. However, most bulk deconvolution methods infer cell-type composition while treating cell types independently. Methods In this paper, we develop CrosstalkIn, a crosstalk-aware bulk deconvolution framework th...

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Literature Corpus work
101311e3-d2f0-542b-91cd-ab15e5bfb05e
DOI
10.21203/rs.3.rs-9550942/v1
Open publication

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CrosstalkIn: Crosstalk-aware inference of tumor microenvironment cell infiltrationDOI 10.21203/rs.3.rs-9550942/v1
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