Single-cell transcriptome-based multilayer network biomarker for predicting prognosis and therapeutic response of gliomas

Abstract excerpt

Occurrence and development of cancers are governed by complex networks of interacting intercellular and intracellular signals. The technology of single-cell RNA sequencing (scRNA-seq) provides an unprecedented opportunity for dissecting the interplay between the cancer cells and the associated microenvironment. Here we combined scRNA-seq data with clinical bulk gene expression data to develop a computational...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Glioma Diagnosis and Treatment
• Share to Neuroinflammation and Neurodegeneration Mechanisms
• Share to Single-cell and spatial transcriptomics