Article

Contemporary HIV-1 envelope pseudovirus panels for detecting and assessing B cell lineages with broadly neutralizing antibody potential

2025-11-24

Abstract excerpt

<h4>ABSTRACT</h4> Although a protective HIV-1 vaccine has not yet been realized, significant progress has been made in vaccine designs that trigger B cell lineages with potential to produce broadly neutralizing antibodies (bnAbs). Advancing these strategies by optimizing vaccine boosting regimens requires early detection of maturing antibodies with neutralizing activity against native envelope glycoprotein (Env)...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6bccf9ec-0117-5916-8d31-40a782d22cb4
DOI: 10.1101/2025.11.21.689752

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Contemporary HIV-1 envelope pseudovirus panels for detecting and assessing B cell lineages with broadly neutralizing antibody potentialDOI 10.1101/2025.11.21.689752Read

Profiling a large HIV-1 elite neutralizer cohort reveals remarkable CD4bs bNAb for HIV-1 prevention and therapySemantic proximity Read

Determinants of HIV-1 broadly neutralizing antibody induction.Semantic proximity Read

Harnessing the protective potential of HIV-1 neutralizing antibodiesSemantic proximity Read

HIV-1 Envelope Glycoproteins from Diverse Clades Differentiate Antibody Responses and Durability among Vaccinees.Semantic proximity Read

Vaccine Induction of Heterologous HIV-1 Neutralizing Antibody B Cell Lineages in HumansSemantic proximity Read

Antibodies Targeting the Envelope of HIV-1.Semantic proximity Read

Analysis of Memory B Cell Responses and Isolation of Novel Monoclonal Antibodies with Neutralizing Breadth from HIV-1-Infected IndividualsSemantic proximity Read

Neutralizing Activity of Broadly Neutralizing Anti-HIV-1 Antibodies against Clade B Clinical Isolates Produced in Peripheral Blood Mononuclear CellsSemantic proximity Read

The Use of Broadly Neutralizing Antibodies (bNAbs) in HIV-1 Treatment and PreventionSemantic proximity Read

Next-generation bNAbs for HIV-1 cure strategiesSemantic proximity Read

Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C InfectionSemantic proximity Read

Shared HIV envelope-specific B cell clonotypes induced by a pox-protein vaccine regimenSemantic proximity Read