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Article

Systematic analysis of human antibody response to ebolavirus glycoprotein reveals high prevalence of neutralizing public clonotypes

2022-01-13

Abstract excerpt

<h4>SUMMARY</h4> Understanding the human antibody response to emerging viral pathogens is key to epidemic preparedness. As the size of the B cell response to a pathogenic virus protective antigen is undefined, we performed deep paired heavy and light chain sequencing in EBOV-GP specific memory B cells, allowing analysis of the ebolavirus-specific antibody repertoire both genetically and functionally. This approac...

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Literature Corpus work
1eaf9c50-c4bd-5939-816f-cb95d3919c56
DOI
10.1101/2022.01.12.476089
Open publication

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Systematic analysis of human antibody response to ebolavirus glycoprotein reveals high prevalence of neutralizing public clonotypesDOI 10.1101/2022.01.12.476089
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