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Modeling Western Pacific Amyotrophic Lateral Sclerosis and Parkinsonism–dementia Complex with Microglia Containing Cerebral Organoids Derived from Induced Pluripotent Stem Cells

2021-08-08

Abstract excerpt

<h4>ABSTRACT</h4> Western Pacific Amyotrophic Lateral Sclerosis and Parkinsonism–dementia Complex (ALS-PDC) is a neurodegenerative disease linked to the traditional consumption of cycad seeds by the Chamorro people of Guam. Little is known about the etiological role of cycad toxin in ALS-PDC. Patient-derived induced pluripotent stem cells were derived from age- and sex-matched affected and unaffected patient lymp...

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Literature Corpus work
0ff92eb0-54ab-5f03-9967-1736654b10ec
DOI
10.1101/2021.08.06.455467
Open publication

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Modeling Western Pacific Amyotrophic Lateral Sclerosis and Parkinsonism–dementia Complex with Microglia Containing Cerebral Organoids Derived from Induced Pluripotent Stem CellsDOI 10.1101/2021.08.06.455467
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