Article

The Hippo pathway controls myofibril assembly and muscle fiber growth by regulating sarcomeric gene expression

2020-10-09

Abstract excerpt

Skeletal muscles are composed of gigantic cells called muscle fibers, packed with force-producing myofibrils. During development the size of individual muscle fibers must dramatically enlarge to match with skeletal growth. How muscle growth is coordinated with growth of the contractile apparatus is not understood. Here, we use the large Drosophila flight muscles to mechanistically decipher how muscle fiber growth...

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Literature Corpus work: 0fe45a86-3e42-5d9e-a312-26a608c06bd6
DOI: 10.1101/2020.10.08.330951

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