Article

KLHL41 orchestrates sarcomere assembly and size to drive skeletal muscle hypertrophy <i>in vivo</i>

2025-06-01

Abstract excerpt

<h4>ABSTRACT</h4> Sarcomere assembly and growth are fundamental processes essential for the development, function, and repair of skeletal muscle. However, the mechanisms underlying sarcomere formation and assembly in vivo , which are critical for the formation of functional myofibers in vertebrates, remain poorly understood. Defects in sarcomeres contribute to muscle dysfunction in numerous genetic and acquired...

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Literature Corpus work: 82251c01-e27e-5b3d-9592-a84b2e04dd31
DOI: 10.1101/2025.05.30.655367

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