Article

Comparative Genomic and Functional Profiling of ECM-Targeting Enzymes in <i>Bacteroides</i> , a Key Genus of the Human Gut Microbiome

2026-03-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose: </h4> The human extracellular matrix (ECM) provides essential cues for intestinal homeostasis. While most studies focus on ECM degradation by host cells, our prior work suggests that commensal gut microbes may also contribute to these remodeling processes. Here, we continue exploring this novel dimension of host-microbe interactions by profiling the proteolytic diversity and substra...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a908adb4-99fa-5cb0-8f3a-c676581e8440
DOI: 10.64898/2026.03.04.709643

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comparative Genomic and Functional Profiling of ECM-Targeting Enzymes in <i>Bacteroides</i> , a Key Genus of the Human Gut MicrobiomeDOI 10.64898/2026.03.04.709643Read

Diversity, Structures, and Collagen-Degrading Mechanisms of Bacterial Collagenolytic Proteases.Semantic proximity Read

Metaproteomics reveals potential signatures of disease-specific alterations in the gut microbial proteolytic events in inflammatory bowel diseaseSemantic proximity Read

Substrate recognition and cleavage by mucin degrading <i>O</i> -glycopeptidases from the gut microbe <i>Bacteroides caccae</i>Semantic proximity Read

Chemoproteomic identification of a dipeptidyl peptidase 4 (DPP4) homolog in <i>Bacteroides thetaiotaomicron</i> important for envelope integrity and fitnessSemantic proximity Read

Chemoproteomic identification of a dipeptidyl peptidase 4 (DPP4) homolog in Bacteroides thetaiotaomicron important for envelope integrity and fitnessSemantic proximity Read

Matrix Dynamics and Microbiome Crosstalk: Matrix Metalloproteinases as Key Players in Disease and TherapySemantic proximity Read

A microbiome meta-transcriptomics pipeline identifies a novel human neutrophil elastase inhibitor that protects the colonic epithelial barrierSemantic proximity Read

Large-scale computational analyses of gut microbial CAZyme repertoires enabled by CaymanSemantic proximity Read

Protease activities of vaginal <i>Porphyromonas</i> species disrupt coagulation and extracellular matrix in the cervicovaginal nicheSemantic proximity Read

Genomic Insights into the Distribution of Peptidases and Proteolytic Capacity among Prevotella and Paraprevotella SpeciesSemantic proximity Read

Identification and study of Prolyl Oligopeptidases and related sequences in bacterial lineagesSemantic proximity Read