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Forward genetic screen in zebrafish identifies new fungal regulators that limit host-protective <i>Candida</i> -innate immune interaction

2025-02-15

Abstract excerpt

Candida is one of the most frequent causes of bloodstream infections, and our first line of defense against these invasive infections is the innate immune system. The early immune response is critical in controlling C. albicans infection, but C. albicans has several strategies to evade host immune attack. Phagocytosis of C. albicans blocks hyphal growth, limiting host damage and virulence, but how C. albicans...

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Identifiers and source

Literature Corpus work
c53dfc7c-a478-534e-a9fd-abdaa8ce4c8e
DOI
10.1101/2025.02.14.638315
Open publication

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Forward genetic screen in zebrafish identifies new fungal regulators that limit host-protective <i>Candida</i> -innate immune interactionDOI 10.1101/2025.02.14.638315
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