Article

A roadmap for enriching rare cell populations from human post-mortem brain, demonstrated by 100% microglial purity

2026-07-22

Abstract excerpt

Understanding brain disease requires studying the specific cell types that drive each condition: microglia in Alzheimer’s, dopaminergic neurons in Parkinson’s, motor neurons in ALS, and many others. For most of these rare populations, protocols to isolate them from human post-mortem brain at the required purity have never been developed. The shared hurdles are reliable nuclear markers, compatible fluorescent dyes,...

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Literature Corpus work: 0f73a57f-f119-5f4b-885b-0a3aa9e3b54e
DOI: 10.64898/2026.07.19.739421

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