Article

Sex-Specific Structural Vulnerability in Alzheimer’s Disease: Insights from APOE ε 4-Negative Patients

2026-07-21

Abstract excerpt

<h4>Background: </h4> The interaction between sex, APOE ε4 status, and clinical progression in Alzheimer’s Disease (AD) remains a subject of debate. While females are often considered at higher risk for AD, the underlying structural neuroanatomical trajectories and how they are modulated by genotype are not fully elucidated. This study aims to evaluate how sex and the APOE ε4 genotype interact to influence longitu...

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Literature Corpus work: 0f6b4fe2-e843-5bbd-bc2b-a4629daf2e9d
DOI: 10.20944/preprints202607.1599.v1

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