Article
Apical-Out Human Airway Organoids Modeling SARS-CoV-2 Infection
14 May 2023
Abstract excerpt
The respiratory epithelium, particularly the airway epithelium, is the primary infection site for respiratory pathogens. The apical surface of epithelial cells is constantly exposed to external stimuli including invading pathogens. Efforts have been made to establish organoid cultures to recapitulate the human respiratory tract. However, a robust and simple model with an easily accessible apical surface would...
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