Article

A prevalent focused human antibody response to the influenza hemagglutinin head interface

2020-12-28

Abstract excerpt

<h4>ABSTRACT</h4> Novel animal influenza viruses emerge, initiate pandemics and become endemic seasonal variants that have evolved to escape from prevalent herd immunity. These processes often outpace vaccine-elicited protection. Focusing immune responses on conserved epitopes may impart durable immunity. We describe a focused, protective antibody response, abundant in memory and serum repertoires, to a conserved...

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Identifiers and source

Literature Corpus work: 0f564e68-0900-5421-b015-c0276f68f9ad
DOI: 10.1101/2020.12.28.424595

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