Article

Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies

2024-10-25

Abstract excerpt

<h4>ABSTRACT</h4> Monoclonal antibodies (mAbs) targeting the influenza hemagglutinin (HA) have the potential to be used as prophylactics or templates for next-generation vaccines that provide broad protection. Here, we isolated broad, subtype-neutralizing mAbs from human B cells targeting the H1 or H3 HA head as well as a unique mAb targeting the stem. The H1 mAbs target the previously defined lateral patch epito...

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Identifiers and source

Literature Corpus work: 09f0df86-8855-5b4b-ad37-70c3a3f92fb6
DOI: 10.1101/2024.10.22.619298

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