Article

Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface

2021-01-03

Abstract excerpt

<h4>SUMMARY</h4> Broadly reactive antibodies targeting the influenza A hemagglutinin (HA) head domain are thought to be rare and to require extensive somatic mutations or unusual structural features to achieve breadth against divergent HA subtypes. Here we describe common genetic and structural features of diverse human antibodies from several individuals recognizing the trimer interface (TI) of the influenza HA...

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Literature Corpus work: 6ef7267a-1022-578d-b392-8d7526069ec2
DOI: 10.1101/2020.12.31.424868

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