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Assessing the protective potential of H1N1 influenza virus hemagglutinin head and stalk antibodies in humans

2018-11-26

Abstract excerpt

Seasonal influenza viruses are a major cause of human disease worldwide. Most neutralizing antibodies (Abs) elicited by influenza viruses target the head domain of the hemagglutinin (HA) protein. Anti-HA head Abs can be highly potent, but they have limited breadth since the HA head is variable. There is great interest in developing new universal immunization strategies that elicit broadly neutralizing Abs against...

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Literature Corpus work
533ae5fa-432c-5490-b499-81024e30a00b
DOI
10.1101/478222
Open publication

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Assessing the protective potential of H1N1 influenza virus hemagglutinin head and stalk antibodies in humansDOI 10.1101/478222
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