Article
Identification of long non-coding RNAs involved in neuronal development and intellectual disability.
Scientific reports - 20 Jun 2016
D'haene Eva, Jacobs Eva Z, Volders Pieter-Jan, De Meyer Tim, Menten Björn, Vergult Sarah
Abstract excerpt
Recently, exome sequencing led to the identification of causal mutations in 16-31% of patients with intellectual disability (ID), leaving the underlying cause for many patients unidentified. In this context, the noncoding part of the human genome remains largely unexplored. For many long non-coding RNAs (lncRNAs) a crucial role in neurodevelopment and hence the human brain is anticipated. Here we aimed at...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.