Article

Establishment and stability of the latent HIV-1 DNA reservoir

2016-05-18

Abstract excerpt

HIV-1 infection currently cannot be cured because the virus persists as integrated proviral DNA in long-lived cells despite years of suppressive antiretroviral therapy (ART). To characterize establishment, turnover, and evolution of viral DNA reservoirs we deep-sequenced the p17gag region of the HIV-1 genome from samples obtained after 3-18 years of suppressive ART from 10 patients. For each of these patients, who...

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Literature Corpus work: 0efeb13c-addd-5793-819c-612e25d78000
DOI: 10.1101/053983

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