Article
HIV Proviral Burden, Genetic Diversity, and Dynamics in Viremic Controllers Who Subsequently Initiated Suppressive Antiretroviral Therapy.
mBio - 21 Dec 2021
Omondi F Harrison, Sudderuddin Hanwei, Shahid Aniqa, Kinloch Natalie N, Jones Bradley R, Miller Rachel L, Tsai Olivia, MacMillan Daniel, Trocha Alicja, Brockman Mark A, Brumme Chanson J, Joy Jeffrey B, Liang Richard, Walker Bruce D, Brumme Zabrina L
Abstract excerpt
Curing HIV will require eliminating the reservoir of integrated, replication-competent proviruses that persist despite antiretroviral therapy (ART). Understanding the burden, genetic diversity, and longevity of persisting proviruses in diverse individuals with HIV is critical to this goal, but these characteristics remain understudied in some groups. Among them are viremic controllers-individuals who naturally...
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