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Article

Deep Molecular Characterization of HIV-1 Dynamics under Suppressive HAART

27 Oct 2011

Abstract excerpt

In order to design strategies for eradication of HIV-1 from infected individuals, detailed insight into the HIV-1 reservoirs that persist in patients on suppressive antiretroviral therapy (ART) is required. In this regard, most studies have focused on integrated (proviral) HIV-1 DNA forms in cells circulating in blood. However, the majority of proviral DNA is replication-defective and archival, and as such, has...

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PMID: 22046128
DOI: 10.1371/journal.ppat.1002314

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