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Article

Establishment and stability of the latent HIV-1 DNA reservoir.

eLife - 15 Nov 2016

Brodin Johanna, Zanini Fabio, Thebo Lina, Lanz Christa, Bratt Göran, Neher Richard A, Albert Jan

Abstract excerpt

HIV-1 infection cannot be cured because the virus persists as integrated proviral DNA in long-lived cells despite years of suppressive antiretroviral therapy (ART). In a previous paper (Zanini et al, 2015) we documented HIV-1 evolution in 10 untreated patients. Here we characterize establishment, turnover, and evolution of viral DNA reservoirs in the same patients after 3-18 years of suppressive ART. A median of...

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Identifiers

PMID: 27855060
DOI: 10.7554/eLife.18889
PMCID: PMC5201419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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