Article

Deciphering the Genomic Landscape of Renal Cell Carcinoma Brain Metastases

2026-05-06

Abstract excerpt

<h4>ABSTRACT</h4> Brain metastases from renal cell carcinoma (RCC) remain a major cause of morbidity and mortality, yet the genomic features associated with metastatic dissemination remain poorly understood. Whole-exome sequencing was performed on 72 RCC brain metastasis samples with matched normal. To identify candidate genomic alterations associated with brain metastasis, the genomic alterations detected in the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0ef10ad6-d002-5b0c-8024-63dfe8f6e0e0
DOI: 10.64898/2026.05.02.722447

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Deciphering the Genomic Landscape of Renal Cell Carcinoma Brain MetastasesDOI 10.64898/2026.05.02.722447Read

Sequencing brain metastases and opportunities for targeted therapies.Semantic proximity Read

Genomic profiling of brain metastases: current knowledge and new frontiers.Semantic proximity Read

Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets.Semantic proximity Read

Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance.Semantic proximity Read

Comparative genomic profiling identifies targetable brain metastasis drivers in non-small cell lung cancerSemantic proximity Read

Multilayered molecular profiling supported the monoclonal origin of metastatic renal cell carcinomaSemantic proximity Read

Single-Cell Atlas of Renal Cell Carcinoma Brain Metastasis Uncovers Mechanisms of Immune Dysfunction and ResistanceSemantic proximity Read

Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma.Semantic proximity Read

Whole-Exome Sequencing Identifies Somatic Mutations Associated With Lung Cancer Metastasis to the BrainSemantic proximity Read

Multi-omic molecular profiling reveals potentially targetable abnormalities shared across multiple histologies of brain metastasisSemantic proximity Read

Whole-exome sequencing identifies somatic mutations associated with lung cancer metastasis to the brainSemantic proximity Read

Sinle-Cell Transcriptomics and Machine Learning Algorithms Unveil Metastasis-Associated Cellular Subtypes and Prognostic Signatures in Colorectal CancerSemantic proximity Read