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Article

Clinical and Genomic Phenotype of Brain Metastasis in Nasopharyngeal Carcinoma.

Molecular carcinogenesis - 1 Feb 2025

Peng Ying-Peng, Yang Shuai, He Jianzhong, Liu Qiaodan, Li Xuanzi, Kong Fan-Gen, Wang Si-Yang, Liu Ye

Abstract excerpt

Brain metastasis in nasopharyngeal carcinoma is a rare but poor prognosis clinical problem. This study aims to investigate the clinical characteristics and identify the genomic profiling of nasopharyngeal carcinoma brain metastasis. Patients with a diagnosis of nasopharyngeal carcinoma who visited at the Fifth Affiliated Hospital of Sun Yat-sen University since January 2013 to December 2023 were retrospectively...

Read the complete abstract on PubMed

Topics

Humans
Nasopharyngeal Carcinoma
Male
Female
Brain Neoplasms
Nasopharyngeal Neoplasms
Middle Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Adult

Retrospective Studies

Phenotype

DNA Copy Number Variations

Biomarkers, Tumor

Prognosis

Mutation

Aged

Polymorphism, Single Nucleotide

Genomics

Source

Identifiers

PMID: 39575660
DOI: 10.1002/mc.23853

Genes

PTEN
FGF19
FGF3
FGF4
KMT2C
NFKBIA
NOTCH1
TP53

Provenance

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