Article

Comparative genomic profiling identifies targetable brain metastasis drivers in non-small cell lung cancer

2022-02-11

Abstract excerpt

<title>Abstract</title> <p>Brain metastases (BM) severely impact the prognosis and quality of life of patients with non-small cell lung cancer (NSCLC). To identify targetable drivers of NSCLC-BM, we profiled somatic copy number alterations (SCNAs) in 51 matched pairs of primary NSCLC and BM samples from 33 patients with lung adenocarcinoma (LUAD) and 18 patients with lung squamous cell carcinoma (LUSC). BM consis...

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Literature Corpus work: 7144ff7d-03e6-5607-8a02-78b4ba82da2a
DOI: 10.21203/rs.3.rs-1320380/v1

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