Article

CRY1 fuels resistance to T cell-based immunotherapy in NANOGhigh cancers

2025-01-08

Abstract excerpt

<title>Abstract</title> <p> Cancer immunotherapies, including immune checkpoint blockade (ICB), have marked a significant breakthrough in cancer treatment but their clinical efficacy is limited in immune-resistant tumors. Previously, we found that immunotherapy-mediated immune selection enriches immune-resistant tumors with both tumor-intrinsic and -extrinsic refractory phenotypes via the transcriptional inducti...

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Literature Corpus work: 0ed957e1-dd76-58f6-bd83-9f36364de27f
DOI: 10.21203/rs.3.rs-5658722/v1

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