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Article

API5 confers cancer stem cell-like properties through the FGF2-NANOG axis

16 Jan 2017

Abstract excerpt

Abstract Immune selection drives the evolution of tumor cells toward an immune-resistant and cancer stem cell (CSC)-like phenotype. We reported that apoptosis inhibitor-5 (API5) acts as an immune escape factor, which has a significant role in controlling immune resistance to antigen-specific T cells, but its functional association with CSC-like properties remains largely unknown. In this study, we demonstrated...

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PMID: 28092370
DOI: 10.1038/oncsis.2016.87

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