Article
Cancer vaccination drives Nanog-dependent evolution of tumor cells toward an immune-resistant and stem-like phenotype.
Cancer research - 1 Apr 2012
Noh Kyung Hee, Lee Young-Ho, Jeon Ju-Hong, Kang Tae Heung, Mao Chih-Ping, Wu T-C, Kim Tae Woo
Abstract excerpt
Due to the exquisite specificity and potency of the immune system, vaccination is in theory the most precise and powerful approach for controlling cancer. However, current data from clinical trials indicate that vaccination rarely yields significant benefits for cancer patients in terms of tumor...
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