Article
NANOG helps cancer cells escape NK cell attack by downregulating ICAM1 during tumorigenesis
16 Oct 2019
Abstract excerpt
BACKGROUND: At the beginning of tumorigenesis, newly born cancer cells must successfully avoid attack by the immune system. Although most abnormal cells are efficiently identified and destroyed by the immune system, particularly by NK cells, the molecular mechanisms by which newly born cancer cells evade NK cell surveillance are not fully understood. METHODS: NK cell resistance of highly tumorigenic population of...
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