Article

The genetic architecture of changes in adiposity during adulthood

2023-01-11

Abstract excerpt

Obesity is a heritable disease, characterised by excess adiposity that is measured by body mass index (BMI). While over 1,000 genetic loci are associated with BMI, less is known about the genetic contribution to adiposity trajectories over adulthood. We derive adiposity-change phenotypes from 1.5 million primary-care health records in over 177,000 individuals in UK Biobank to study the genetic architecture of weig...

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Literature Corpus work: 0ed075ea-6388-5636-8297-48cef8919904
DOI: 10.1101/2023.01.09.23284364

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