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Article

Genetic influence on within-person longitudinal change in anthropometric traits in the UK Biobank.

Nature communications - 6 May 2024

Kemper Kathryn E, Sidorenko Julia, Wang Huanwei, Hayes Ben J, Wray Naomi R, Yengo Loic, Keller Matthew C, Goddard Michael, Visscher Peter M

Abstract excerpt

The causes of temporal fluctuations in adult traits are poorly understood. Here, we investigate the genetic determinants of within-person trait variability of 8 repeatedly measured anthropometric traits in 50,117 individuals from the UK Biobank. We found that within-person (non-directional) variability had a SNP-based heritability of 2-5% for height, sitting height, body mass index (BMI) and weight (P ≤...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38710707
DOI: 10.1038/s41467-024-47802-7
PMCID: PMC11074304

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