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Article

Longitudinal Analysis of Genetic Susceptibility and BMI Throughout Adult Life.

Diabetes - 1 Feb 2018

Song Mingyang, Zheng Yan, Qi Lu, Hu Frank B, Chan Andrew T, Giovannucci Edward L

Abstract excerpt

Little is known about the genetic influence on BMI trajectory throughout adulthood. We created a genetic risk score (GRS) comprising 97 adult BMI-associated variants among 9,971 women and 6,405 men of European ancestry. Serial measures of BMI were assessed from 18 (women) or 21 (men) years to 85 years of age. We also examined BMI change in early (from 18 or 21 to 45 years of age), middle (from 45 to 65 years of...

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Identifiers

PMID: 29212779
DOI: 10.2337/db17-1156
PMCID: PMC5780056

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