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Integrated analysis of genomics, longitudinal metabolomics, and Alzheimer’s risk factors among 1,111 cohort participants

2018-10-05

Abstract excerpt

Although Alzheimer’s disease (AD) is highly heritable, genetic variants known to be associated with AD only explain a small proportion of its heritability. Genetic factors may only convey disease risk in individuals with certain environmental exposures, suggesting that a multi-omics approach could reveal underlying mechanisms contributing to complex traits, such as AD. We developed an integrated network to investi...

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Literature Corpus work
47aa1da6-5bf3-5db1-ba27-866811902abe
DOI
10.1101/436923
Open publication

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Integrated analysis of genomics, longitudinal metabolomics, and Alzheimer’s risk factors among 1,111 cohort participantsDOI 10.1101/436923
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