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Molecular landscape of the overlap between Alzheimer’s disease and somatic insulin-related diseases

28 Oct 2024

Abstract excerpt

Alzheimer's disease (AD) is a multifactorial disease with both genetic and environmental factors contributing to its etiology. Previous evidence has implicated disturbed insulin signaling as a key mechanism that plays a role in both neurodegenerative diseases such as AD and comorbid somatic diseases such as diabetes mellitus type 2 (DM2). In this study, we analysed available genome-wide association studies...

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PMID: 39465382
DOI: 10.1186/s13195-024-01609-2

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